Understanding Hemp and the Endocannabinoid System
What is CBD?
Cannabidiol CBD – is a cannabis compound that has significant benefits, but does not make people feel “high.” The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil.
What is Full-Spectrum
Full-spectrum hemp oil refers to when the pure oil extracted from hemp contains all the cannabinoids and compounds found in the original hemp plant. Unlike isolating the CBD, full-spectrum hemp oil contains an array of cannabinoids, as well as many essential vitamins and minerals, fatty acids, protein, chlorophyll, fiber, flavonoids, and terpenes that act synergistically in the body thereby creating what is know at the “Entourage effect”
Full-spectrum hemp oil contains dozens of the plant’s cannabinoids. The most abundant cannabinoid found in hemp oil is cannabidiol (CBD), the non-psychoactive compound shown to have many benefits in studies. CBD makes up over 90% of the cannabinoid content in full-spectrum hemp oil.
Other more major cannabinoids found in full-spectrum include Cannanigerol (CBG), tetrahydrocannabinol (THC), and cannabinol (CBN).
How Does It Work?
The body has a naturally occurring Endocannabinoid System or ECS. Cannabinoids bind to the receptors in our body. There are 3 known receptors: CB1 and CB2 TRPV1 receptors. These receptors are abundant within our body, even the skin. Our ECS system work on a process called Binding Affinity. Once attracted binding affinity refers to how a compound binds (or communicates) to a receptor, either blocking (antagonist) or increasing cells activity (agonist); therefore, starting a reaction. They control many aspects of our body’s internal environment, through mood, emotions, pain, and even how our bodies respond to illness and inflammation. Even though humans produce their own endocannabinoids, cannabis consumption in the supplemental forms and methods being produced are proving beneficial when we feed our bodies cannabinoids. It is due to the specific location and mechanism within our bodies in need that emerging evidence and observations are being discovered with the use of the cannabis plant.
CB1: Present in the central nervous system (CNS) which abundantly in the nerve cells of our brain and spinal cord. These areas moderate pleasure, cognition, memory and how we move.
CB2: Present in the White blood cells and spleen. Beneficial to helping boost and regulate our immune systems.
TRPV1: Widespread throughout the body, and are highly sensitive to noxious stimuli- which means they react very strongly to things that cause us pain. In fact, research indicates that they may have plenty to do with the pain we feel from inflammation. Chronic inflammation is a precursor to many diseases.
Many stimuli are found to act on ion channels present in our bodies, including TRPV channels. Found on pain neurons, when the channels are activated, the signal induced is interpreted in the brain and helps to relive pain.
The major reason for the usage of cannabinoids, psychoactive or not, is their ability to elicit a decrease in pain sensitivity. For both chronic or acute pain, TRPV1 has been implicated in the overall integration of pain signals in both the peripheral and central nervous systems.
CB1 helps regulates our emotional and cognitive perception
CB2 moderates our anti-inflammatory and immune response
TRPV1 is what helps alerts our body when something is terribly wrong- an alarm system so to speak.
These all work together to help us perceive our general state of well being for an overall improvement to our health and wellness.